In a statement Amazon said that the new positions would be permanent hires and open to "people with all levels of experience, training and skills, from software developers and engineers to warehouse workers".
Unemployment in Italy stands at nearly 11 per cent, according to the latest figures from national statistics agency Istat.
That number spikes to nearly 20 per cent for those aged between 15 and 34 and just under 32 per cent for the 15-24 year age range.
Economic growth in Italy has lagged behind the rest of the eurozone in recent years.
This year the country is forecast to see 1.5 percent economic growth, compared to 2.3 per cent for the bloc as a whole.
On Wednesday Amazon also announced that it would be bringing 2,500 jobs to the United Kingdom, boosting its workforce there to 27,500 people.